As for me, I would save the column layout when the form is closed. If you want to do this right after every interactive change of a column width or order, use the ColWidthEndChange and ColHdrEndDrag events.
Just FYI if you didn't know it: the LayoutObject property can help you a lot in saving/restoring the column layout.
Edited by user
2018-12-12T14:55:17Z
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Reason: Not specified