We have fixed this problem in iGrid 6.5 released today. The problem was in the dynamic content events (CellDynamicText, CellDynamicFormatting, ...) raised for every cell. This problem was especially noticeable in Microsoft Access - VB6 apps did not suffer from this problem. Now all those dynamic content events are turned off by default, and the performance of AutoWidthCol in MS Access is good enough.
BTW, iGrid 6.5 also introduces one more method to do the auto-width work for all columns in one call - it's AutoWidthCols.